Present day round-the-clock lifestyle appears to ruin metabolism, learning and behavior in ways that we have just started to understand.

Researchers led by Ilia Karatsoreos of the Hatch Lab of Neuroendocrinology, from Rockefeller University, housed mice for 10 weeks in 20-hour light-dark cycles at odds along with their natural 24-hour circadian cycle.

They have identified that after six weeks, the disrupted mice got fatter, which showed that comparatively less mental flexibility and they were more impulsive than mice kept on their natural schedule, according to the journal Proceedings of the National Academy of Sciences reports.

The circadian system is like a ‘web,’ having rhythms at the molecular level which drives rhythms at the cellular level, which in the end results in rhythms at the tissue level. Consequently it can lead to a cascading set of effects throughout the whole organism and they want to understand how exactly that takes place, according to Karatsoreos.

According to researchers, this cascade may affect how an individual, whether animal or human, replies to infection or high fat food. Both are ubiquitous realities of modern life.
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